Deconstructing autism: from unitary syndrome to contributory developmental endophenotypes
نویسندگان
چکیده
منابع مشابه
Deconstructing psychiatric disorders, Part 1. Genotypes, symptom phenotypes, and endophenotypes.
BRAINSTORMS is a monthly section of The Journal of Clinical Psychiatry aimed at providing updates of novel concepts emerging from the neurosciences that have relevance to the practicing psychiatrist. From the Neuroscience Education Institute in Carlsbad, Calif., and the Department of Psychiatry at the University of California San Diego. Reprint requests to: Stephen M. Stahl, M.D., Ph.D., Editor...
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BACKGROUND Autism spectrum conditions (ASC) are associated with deficits in social interaction and communication, alongside repetitive, restricted, and stereotyped behavior. ASC is highly heritable. The gamma-aminobutyric acid (GABA)-ergic system has been associated consistently with atypicalities in autism, in both genetic association and expression studies. A key component of the GABA-ergic s...
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ژورنال
عنوان ژورنال: International Review of Psychiatry
سال: 2018
ISSN: 0954-0261,1369-1627
DOI: 10.1080/09540261.2018.1433133